Best Vertical Mouses

If you work for 8+ hours on your computer and get a sprained wrist by the end of the day then you need a vertical mouse. Vertical mouse, where your wrist’s comfort is king. Let’s dive right into the best vertical mouses on the market, and discover how they can revolutionize your computing experience.

We surveyed 100 plus best vertical mouse users and based on their opinion we have curated a list of the best 5 vertical mouses for you. Here’s the list of best vertical mouses:

  1. Logitech MX Vertical
  2. Anker Wireless Vertical Mouse
  3. Evoluent VerticalMouse 4
  4. J-Tech Digital V628
  5. Adesso iMouse E9

Logitech MX Vertical: The Ergonomic Champion

Logitech MX Vertical Wireless Mouse - best vertical mouse overall

First up, the Logitech MX Vertical – an absolute unit of a mouse. This beauty has an ergonomic design that will make your wrist sing hallelujah.

With its customizable buttons and adjustable DPI settings, it’s perfect for long gaming sessions or tackling those pesky spreadsheets at work. Trust us, this one’s a game changer.


  • Adjustable DPI settings (400 to 4000)
  • 4 customizable buttons
  • Cross-computer control and file sharing
  • Rechargeable battery lasting up to 4 months


  • Higher price tag
  • Heavier feel
  • Limited customization for Linux users

Anker Wireless Vertical Mouse: Editor’s Choice

Say hello to the Anker Wireless Vertical Mouse, the mouse that’ll be your wrist’s BFF. Sporting a unique handshake grip design, this baby takes pressure off your wrist and forearm, making it perfect for long hours in front of the computer. And with a sleek, modern look, it’ll be the envy of all your coworkers.


  • Handshake grip design for ultimate comfort
  • 3 adjustable DPI settings (800 to 1600)
  • Plug-and-play compatibility with most devices
  • Energy-saving auto-sleep mode


  • Requires AAA batteries
  • Only 5 buttons

Evoluent VerticalMouse 4: The Ergonomic Powerhouse

Meet the Evoluent VerticalMouse 4, a vertical mouse designed for those who want it all. It’s got a sleek design, with an ultra-precise laser sensor for unmatched accuracy. If you’re a multitasker, the VerticalMouse 4 is your new bestie.


  • Sculpted design for maximum comfort
  • Adjustable DPI settings (800 to 2600)
  • 6 programmable buttons
  • Wired and wireless versions available


  • Expensive
  • Learning curve for unique shape

J-Tech Digital V628: Best Budget Option

J-Tech Digital V628 wallet-friendly vertical mouse is perfect for those on a budget who still want to enjoy the benefits of a vertical mouse. It’s got an ergonomic design, customizable DPI settings, and a no-slip grip. You’ll wonder how you ever lived without it.


  • Ergonomic design
  • 3 adjustable DPI settings (800 to 1600)
  • No-slip grip for added control
  • Removable palm rest


  • Stiff scroll wheel
  • Larger design, not ideal for smaller hands

Adesso iMouse E9: For Lefties

Adesso iMouse E9, a left-handed vertical ergonomic mouse, caught my attention! With its sleek black design and USB connectivity, it fits right in on my desk. The adjustable 4-level DPI switch (800/1200/1600/2400) lets me fine-tune my cursor speed for different tasks, which is super handy

The optical sensor technology allows me to work on glass and even leather surfaces without a mouse pad, which is pretty cool. But what really sets it apart for me are those two internet navigational buttons on the side – they make browsing the web a breeze!


  • Left-handed ergonomic design
  • Adjustable 4-level DPI switch
  • Optical sensor technology (works on various surfaces)
  • Convenient internet navigational buttons


  • A bit pricey

Is Vertical Mouse More Healthy?

Wondering,are vertical mice really healthier for our wrists and hands?” After doing a bit of research, I found out that these ergonomic wonders are designed to keep our hands in a more natural, handshake-like position.

This helps reduce the strain on our wrists and muscles, which in turn lowers the risk of developing issues like carpal tunnel syndrome and other repetitive stress injuries. I’ve gotta say, I’m pretty impressed by this innovative approach to mousing.

With so many people working long hours at computers, it makes total sense to prioritize comfort and well-being. So, I think it’s definitely worth considering a vertical mouse to help keep our hands and wrists in tip-top shape!

What Are The Disadvantages of a Vertical Mouse?

While vertical mice are definitely known for their ergonomic benefits, they’re not without their downsides. One thing that comes to mind is the learning curve. I remember when I first tried one, it took me a while to get used to the grip and the movement, and I found my hand feeling a bit awkward.

Some people might also find vertical mice to be a bit bulkier than their traditional counterparts, which could be a bummer for those with limited desk space. And let’s not forget about the price tag! These ergonomic gadgets can be a bit pricier than your average mouse, which might make some folks think twice before taking the plunge. So, while vertical mice have their perks, it’s important to weigh the pros and cons before diving in headfirst.


So, there you have it – the 5 best vertical mouse to help your wrist. Say goodbye to wrist pain, and hello to ergonomic bliss. Whether you’re a gamer, a busy professional, or just someone who loves to browse the internet, these vertical mice have got you covered.

RankMouseRatingOur Opinion
1Logitech MX Vertical9.5/10Ergonomic champion, adjustable DPI, customizable buttons, cross-computer control, rechargeable
2Anker Wireless Vertical8.5/10Handshake grip design, adjustable DPI, plug-and-play, energy-saving, wireless
3Evoluent VerticalMouse 48.0/10Sculpted design, adjustable DPI, 6 programmable buttons, wired/wireless options
4J-Tech Digital V6287.5/10Budget-friendly, ergonomic design, adjustable DPI, no-slip grip, removable palm rest
5Adesso iMouse E9 (LH)7.0/10Left-handed design, adjustable DPI, optical sensor technology, internet navigational buttons

Related Articles:

Best Vertical Monitors
Best Mouse with Side Scroll
8 Best Gaming Mouses with Side Buttons

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Founder & Chief Editor | + posts

Few years back I started to work from home, I needed a keyboard, I researched mechanical keyboard from A to Z. After that I needed a monitor, after that I needed a mouse, after that I needed desk, chair and other accessories. I did so much research and I figured this can't all go to waste and I started writing about what I know. Keyboards, Monitors, Mouses and other accessories. You can also at WolfofTablet where I cover a lot of stuff about iPads and Android Tablets. In the free time I like to play PS5 and iOS games.

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