8 Best Gaming Mouse with Side Buttons

Are you on the hunt for the ultimate “gaming mouse with side buttons“? Well, look no further! We’ve got you covered with a sensational selection of top gaming mice that boast those oh-so-convenient side buttons.

We tested more than multiple gaming mice with side buttons on the basis of accuracy, adaptability, and unadulterated gaming experience and came up with the following 8 remarkable mice:

  1. Corsair Scimitar RGB Elite
  2. SteelSeries Rival 500
  3. Logitech G604 Lightspeed
  4. HyperX Pulsefire Raid
  5. Roccat Nyth
  6. Razer Naga Pro
  7. ASUS ROG Pugio II
  8. Logitech MX Master 3

Now let’s discuss each gaming mouse with side buttons in detail. 

1. Corsair Scimitar RGB Elite: The Speedy Savior

The Corsair Scimitar RGB Elite will make you feel like you’ve won the gaming lottery. With 12 side buttons that can be adjusted to your preferred position, this mouse is perfect for MMO and MOBA lovers.

Its 18,000 DPI sensor ensures you never miss a click. The icing on the cake? The customizable RGB lighting will make your setup look like a million bucks.


  • 12 adjustable side buttons for customization
  • 18,000 DPI sensor for high precision
  • Customizable RGB lighting


  • May be too large for some users
  • Can be overwhelming for those who prefer fewer buttons

2. SteelSeries Rival 500: The Flex Master

Innovation at its finest, the SteelSeries Rival 500 boasts 15 programmable buttons, including a unique thumb button layout.

The buttons are designed to mimic the natural motion of your fingers, so you can game for hours without feeling like you’ve just completed a thumb wrestling marathon. And with customizable tactile alerts, you’ll know exactly when your cooldowns are ready to roll.


  • 15 programmable buttons
  • Unique thumb button layout
  • Customizable tactile alerts


  • Slightly bulky design
  • Steeper learning curve for button placement

3. Logitech G604 Lightspeed: The Precision Prodigy

The Logitech G604 Lightspeed is the perfect blend of versatility and precision. With six programmable side buttons, this mouse is ideal for gamers who appreciate a clean and clutter-free design.

The HERO 25K sensor means you’ll have no problem achieving pixel-perfect aim, and the option to switch between Lightspeed wireless and Bluetooth connectivity ensures you’re always connected.


  • Six programmable side buttons
  • HERO 25K sensor for accuracy
  • Lightspeed wireless and Bluetooth connectivity


  • Limited RGB lighting customization
  • Some users may prefer more side buttons

4. HyperX Pulsefire Raid: The Underdog

Don’t let the modest price tag fool you – the HyperX Pulsefire Raid packs a punch. With 11 programmable buttons and a Pixart 3389 sensor offering up to 16,000 DPI, this gaming mouse is a force to be reckoned with.

Plus, the comfortable ergonomic design and customizable RGB lighting make it a worthy addition to any gaming setup.


  • Affordable price
  • 11 programmable buttons
  • Comfortable ergonomic design


  • Lower DPI sensor (16,000) compared to some competitors
  • Limited software customization options

5. Roccat Nyth: The Ergonomic Enthusiast

The Roccat Nyth is like the Swiss Army knife of gaming mice. With a whopping 33 possible button combinations and a modular design that lets you customize the grip, this mouse is a dream come true for gamers who crave personalization.

The 12,000 DPI laser sensor ensures you’re always on target, and the Easy-Shift[+] button duplicator gives you even more customization options.


  • 33 possible button combinations
  • Modular design for customizable grip
  • Easy-Shift[+] button duplicator


  • Slightly outdated 12,000 DPI laser sensor
  • Larger and heavier than some competitors

6. Razer Naga Pro: The Programmable Powerhouse

The Razer Naga Pro is a triple threat with three interchangeable side plates for different button layouts. Choose between 2, 6, or 12 buttons, depending on your gaming preferences.

The Focus+ 20K DPI optical sensor guarantees deadly precision, and Razer’s Hyperspeed wireless technology ensures lag-free gameplay. Add in customizable Chroma RGB lighting, and you’ve got a gaming mouse that’s both stylish and powerful.


  • Three interchangeable side plates
  • Focus+ 20K DPI optical sensor
  • Hyperspeed wireless technology


  • Premium price point
  • Swapping side plates may be cumbersome for some users

7. ASUS ROG Pugio II: The Ambidextrous Ace

For all the lefties and ambidextrous gamers out there, we’ve got a treat for you! The ASUS ROG Pugio II is an ambidextrous gaming mouse with configurable side buttons to suit your unique gaming needs.

Sporting a total of 9 programmable buttons and a high-precision 16,000 DPI sensor, this mouse ensures you’re always in control.

The Pugio II also features customizable Aura Sync RGB lighting and a magnetic button design that allows for easy swapping of side button configurations. With this mouse in your arsenal, you’ll be ready to dominate any battlefield, no matter which hand you prefer to use.


  • Ambidextrous design
  • Configurable side buttons
  • 16,000 DPI sensor


  • May not be as comfortable for users with larger hands

And there you have it, folks! Our top 7 gaming mice with side buttons that will not only make your gaming life easier but also more enjoyable.

8. Logitech MX Master 3

Logitech MX Master 3 with side buttons

Logitech MX Master 3 Advanced Wireless Mouse is a true game-changer. The MagSpeed wheel is incredibly fast, precise, and quiet, making scrolling through long documents feel like a breeze. With its Darkfield 4000 DPI sensor, the mouse glides smoothly on any surface, even glass! It’s like magic.

The comfortable design with tactile reference points keeps my hand in the perfect position, making long work sessions much more enjoyable. 

The flow cross-computer control and ability to pair with up to three devices is a lifesaver when I’m multitasking between screens


  • Ultra-fast MagSpeed wheel
  • Precise Darkfield 4000 DPI sensor
  • Comfortable ergonomic design
  • Flow cross-computer control
  • Pairs with up to three devices


  • Not specifically designed for gaming
  • May be too large for some users

Is a gaming mouse with side buttons ergonomic?

When it comes to gaming mice with side buttons, the question of ergonomics is an interesting one. You see, having those extra side buttons can really elevate your gaming experience, providing quick access to crucial commands without having to stretch your fingers too far.

Some gaming mice even offer adjustable button positions, making it possible to tailor the layout to your hand’s size and shape. However, it’s essential to keep in mind that not every gaming mouse with side buttons is created equal.

Some might be too large or small, or perhaps the button layout just doesn’t feel right for your hand. It’s all about finding the perfect balance between functionality and comfort.

Why a gaming mouse has side buttons?

So, why do gaming mice have side buttons, you ask? Well, it all comes down to giving gamers a competitive edge. You see, in the heat of battle, whether you’re raiding dungeons or taking down opponents in a fast-paced shooter, having those side buttons can make a world of difference.

These nifty little additions allow you to access key commands, skills, or weapons without taking your fingers off the essential movement keys, keeping you in control and ready to react at a moment’s notice.

Are all gaming mice with side buttons programmable?

You know, not all gaming mice with side buttons are programmable, but many of them are. Those programmable side buttons truly give you an edge in gaming, allowing you to assign specific commands or macros for quick access. It’s like having a mini keyboard right at your fingertips!

With programmable side buttons, you can execute complex actions with just a single click, giving you the advantage in those intense gaming moments. 


And there you have it, folks! Our top 8 gaming mice with side buttons that will not only make your gaming life easier but also more enjoyable. Here’s a table to help you reach the final verdict.

MouseOur RatingOur Opinion
Corsair Scimitar RGB Elite9.5/1012 adjustable side buttons, 18,000 DPI sensor, customizable RGB lighting
SteelSeries Rival 5009/1015 programmable buttons, unique thumb button layout, customizable tactile alerts
Logitech G604 Lightspeed9.3/10Six programmable side buttons, HERO 25K sensor, Lightspeed wireless & Bluetooth connectivity
HyperX Pulsefire Raid8.5/10Affordable price, 11 programmable buttons, comfortable ergonomic design
Roccat Nyth8.7/1033 possible button combinations, modular design, Easy-Shift[+] button duplicator
Razer Naga Pro9.7/10Three interchangeable side plates, Focus+ 20K DPI sensor, Hyperspeed wireless technology
ASUS ROG Pugio II9/10Ambidextrous design, configurable side buttons, 16,000 DPI sensor
Logitech MX Master 38.8/10MagSpeed wheel, Darkfield 4000 DPI sensor, comfortable design, flow cross-computer control, pairs with 3 devices

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I work from home. To do the best possible job I need the right accessories - the right desk, the right chair, the right keyboard, the right monitor, etc. When I work I want to feel comfortable. I review everything that's related to home desk setup - focusing on Monitors & Keyboards.